The Pattern of Serum Copper and Magnesium in Pregnant Women Covered by Urmia Urban Health Centers and Its Clinical and Nutritional Determinants in the Third Trimester of Pregnancy, 2018

Background: Copper and Magnesium are essential for development of the fetus and maternal health. The aim of this study was to determine the pattern of serum copper in pregnant women in Urmia and its association with some clinical and nutritional factors in the third trimester of pregnancy. Materials and method: In this analytic cross-sectional study, 400 pregnant women in the third trimester were randomly selected from the women who referred to 6 selected health centers for their routine care. It was investigated demographic, nutritional and clinical factors and fasting blood samples were obtained. The data were analyzed using Chi-square, Independent T-test and logistic Regression tests using SPSS 21 software. Results: The serum analysis showed that Magnesium and copper deficiency among studied population were not prevalent but high serum levels of magnesium and copper were seen in 24% and 13% of them respectively. Based on binary logistic regression model outputs, the development of excessive serum magnesium levels was directly correlated with dietary magnesium intake, magnesium supplementation and dietary fiber intake (OR: 1.109; 95% CI: 1.008-1.219) and inversely correlated with total dietary intake of calcium. The high concentration of serum copper was directly associated with dietary intake of copper and negatively associated with total intake of dietary magnesium, iron deficiency anemia (OR: 0.369; 95% CI: 0.166-0.819) and pre-pregnancy BMI. Conclusion: Pregnant women in Urmia probably have high concentrations of serum magnesium in comparison to other parts of the country. It is likely related to consumption of the Mg supplementation.